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بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی
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بهترین سایت شرط بندی ایرانی
بهترین سایت شرط بندی ایرانی

Global Statistics

All countries
695,781,740
Confirmed
Updated on September 26, 2023 9:04 pm
All countries
627,110,498
Recovered
Updated on September 26, 2023 9:04 pm
All countries
6,919,573
Deaths
Updated on September 26, 2023 9:04 pm

Global Statistics

All countries
695,781,740
Confirmed
Updated on September 26, 2023 9:04 pm
All countries
627,110,498
Recovered
Updated on September 26, 2023 9:04 pm
All countries
6,919,573
Deaths
Updated on September 26, 2023 9:04 pm

Antiviral nasal spray may fight coronavirus, study finds

City of Cape Town urges people to leave Kataza the baboon alone

Kataza the baboon. Facebook / Baboon Matters The City of Cape Town has asked the public not to feed a baboon that has relocated to Tokai. The baboon, known as Kataza or SK11, is slowly being integrated into the Tokai troop. Video footage, however, shows humans feeding Kataza. The City of Cape Town has requested that Kataza…

Rassie: There are various benefits for SA rugby to go north

As SA Rugby moves to determine which franchises will go to Europe in future, Rassie Erasmus has noted several potential benefits for the local game should that route be followed.The national director of rugby believes the high world rankings of Wales, Ireland and Scotland mean PRO Rugby is competitive and that fans will eventually identify…

A Once-in-a-Century Climate ‘Anomaly’ Might Have Made World War I Even Deadlier

(John Finney Photography/Moment/Getty Images) An abnormally bad season of weather may have had a significant impact on the death toll from both World War I and the 1918 Spanish flu pandemic, according to new research, with many more lives being lost due to torrential rain and plummeting temperatures. Through a detailed analysis of an ice…

PICS | Truck driver killed in Pinetown after truck ploughs into several cars

A vehicle that was hit in the accident. A truck driver was killed in a horrific sequence of events following an initial crash in Pinetown. While trying to move the truck after the accident, it appeared to lose control. He died after falling out of the truck which ploughed into several cars and a wall.A truck driver…

42 people in court for R56m police vehicle branding scam

Forty-two people have been implicated in a police car branding scam. Forty-two people have been arrested for their alleged involvement in a police vehicle branding scam. They face a range of charges including corruption, fraud, money laundering, theft and perjury.Of these, 22 are serving police members.Forty-two people are set to appear in the Pretoria Magistrate's Court on…

Moms create coronavirus solutions for kids: Why they say their PPE face shields are more effective than cloth masks

Little Lives PPE is helping children and adults reenter the world safely amid the coronavirus pandemic. Dr. Gabrielle Page-Wilson and Alexandra Stanton founded Little Lives PPE to not only maintain the physical health of their children, but to also help children and adults alike maintain their mental health through being able to mitigate risk and safely attend school and work during COVID-19. The two founders discuss why face shields are much more effective than cloth masks in protecting the population from coronavirus.

A nasal spray that may fend off coronavirus has been formulated by researchers at the University of California, San Francisco, according to a report. The researchers are now working to get it clinically tested and manufactured.

The aerosol spray, called AeroNabs, is an antiviral aimed at preventing COVID-19, though it is not a cure, the researchers stated in a release. They added it could be a good weapon against novel coronavirus until a vaccine is found, or a potential alternative for those who don’t respond to a vaccine.

YOUNG CHILDREN WITH CORONAVIRUS MAY CARRY 10 TO 100 TIMES MORE OF VIRUS THAN ADULTS: STUDY

“Far more effective than wearable forms of personal protective equipment, we think of AeroNabs as a molecular form of PPE that could serve as an important stopgap until vaccines provide a more permanent solution to COVID-19,” said Peter Walter, Ph.D., professor of biochemistry and biophysics at UCSF and a Howard Hughes Medical Institute Investigator, in a press release.

“For those who cannot access or don’t respond to SARS-CoV-2 vaccines, AeroNabs could be a more permanent line of defense against COVID-19,” Walter, who is also the AeroNabs co-inventor, added.

The scientists stated in the release that they were inspired by nanobodies, which are like antibodies found in llamas and camels.

“Though they function much like the antibodies found in the human immune system, nanobodies offer a number of unique advantages for effective therapeutics against SARS-CoV-2,” said co-inventor Aashish Manglik, MD, Ph.D., an assistant professor of pharmaceutical chemistry, in a statement.

Coronavirus/COVID-19. (3D Rendering)

Coronavirus/COVID-19. (3D Rendering)
(redit:BlackJack3D/ iStock)

The researchers explained that the SARS-CoV-2 relies on spike proteins to infect human cells.

“They are the essential key that allows the virus to enter our cells,” they said.

The researchers explained that when the coronavirus particle’s activate, the spikes receptors become primed to attach to ACE2 (angiotensin-converting enzyme 2) inhibitors that are found in human cells that line the nasal passageway, lungs and airway. Researchers in the field of coronavirus recently told Fox News that this is the virus’ point of entry.

The authors explained in the report that they developed “single-domain antibodies (nanobodies) that potently disrupt the interaction between the SARS-CoV-2 Spike and ACE2.” They were able to create synthetic nanobodies in a yeast surface and found that the nanobodies bound to the spikes and blocked the ACE2 interaction, thus blocking the virus from invading the host.

CORONAVIRUS: COULD YOUR BODY ALREADY HAVE CELLS THAT RECOGNIZE AND FIGHT IT?

The investigators explained in the news release that the most potent nanobodies act not only like a sheath surrounding the spike receptors, but also like a “molecular mousetrap, clamping down on spike in its closed, inactive state, which adds an additional layer of protection against the spike–ACE2 interactions that lead to infection.”

The nanobodies remained a potent SARS-CoV-2 antiviral when tested in an aerosolized form, according to the news release. These mean it could be practical to administer via a shelf-stable inhaler or nasal spray. This aerosol form could provide a “patient-friendly prophylactic and/or early infection therapeutic agent to stem the worst pandemic in a century,” the researchers said.

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Hot Topics

City of Cape Town urges people to leave Kataza the baboon alone

Kataza the baboon. Facebook / Baboon Matters The City of Cape Town has asked the public not to feed a baboon that has relocated to Tokai. The baboon, known as Kataza or SK11, is slowly being integrated into the Tokai troop. Video footage, however, shows humans feeding Kataza. The City of Cape Town has requested that Kataza…

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(John Finney Photography/Moment/Getty Images) An abnormally bad season of weather may have had a significant impact on the death toll from both World War I and the 1918 Spanish flu pandemic, according to new research, with many more lives being lost due to torrential rain and plummeting temperatures. Through a detailed analysis of an ice…

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City of Cape Town urges people to leave Kataza the baboon alone

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