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بهترین سایت شرط بندی ایرانی
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Global Statistics

All countries
695,781,740
Confirmed
Updated on September 26, 2023 9:04 pm
All countries
627,110,498
Recovered
Updated on September 26, 2023 9:04 pm
All countries
6,919,573
Deaths
Updated on September 26, 2023 9:04 pm

Global Statistics

All countries
695,781,740
Confirmed
Updated on September 26, 2023 9:04 pm
All countries
627,110,498
Recovered
Updated on September 26, 2023 9:04 pm
All countries
6,919,573
Deaths
Updated on September 26, 2023 9:04 pm

20K volunteer for coronvirus exposure in possible ‘human challenge trial’

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A vehicle that was hit in the accident. A truck driver was killed in a horrific sequence of events following an initial crash in Pinetown. While trying to move the truck after the accident, it appeared to lose control. He died after falling out of the truck which ploughed into several cars and a wall.A truck driver…

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More than 20,000 people have signed up to voluntarily be exposed to the novel coronavirus in a yet-to-be formulated “human classified trial.” The trial, being led by a group called 1Day Sooner, is meant to speed up vaccine development, but has no ties to companies currently working on one.

The group is looking for healthy volunteers between the ages of 20 and 45 who have no underlying conditions.

TRUMP CALLS OUSTED HHS OFFICIAL ‘UNHAPPY DISGRUNTLED PERSON,’ DEFENDS HYDROXYCHLOROQUINE TESTS

“We want to recruit as many people as possible who want to do this, and pre-qualify them as likely to be able to participate in challenge trials should they occur,” Josh Morrison, 1Day Sooner co-founder, previously told Nature. “At the same time, we feel that the public policy decisions around challenge trials will be better informed if they highlight the voice of people interested in participating in such trials.”

Human challenge trials deliberately expose volunteers to infection in order to study diseases and possible vaccines or treatments. Similar trials are conducted each year with the seasonal flu. In one instance, St. Louis University’s Center for Vaccine Development offered $3,500 to volunteers who are willing to expose themselves to the influenza virus after receiving either the vaccine or a placebo.

“It is currently uncertain how many people COVID-19 will affect worldwide and at what speed its impacts will be felt,” the 1Day Sooner website said. “Possible outcomes are shaped by interventions like social distancing, the capacity of health systems, potential drug treatments and many other factors. A vaccine may come after the infection has peaked or once effective pharmaceutical treatments have blunted COVID-19’s impact. But it is clear that COVID-19 will continue to alter daily life until an effective vaccine is fully deployed.”

COLORADO SEES FIRST CORONAVIRUS OUTBREAKS CONNECTED TO CHILDCARE CENTERS

As of Thursday, over 20,000 people from 102 countries had signed up to volunteer for the hypothetical trial. Human challenge trials for coronavirus have the support of 35 members of the House of Representatives who wrote to the Food and Drug Administration and the Department of Health and Human Services arguing that they should be allowed.

According to the group’s website, the trial, which has no potential start date and could by some estimates take up to two years to formulate, is aiming to enroll volunteers who are already likely to have been exposed to COVID-19, and they would be isolated in “highly controlled environments under constant observation.” The participants would receive the vaccine candidate or placebo and then be exposed to live coronavirus so that researchers could determine the vaccine candidate’s efficacy.

“If infection is detected, they would be provided with excellent medical treatment,” the group said. “Hopefully pharmaceutical treatments will also be available by the time a study is conducted.”

However, Anna Durbin, a vaccine researcher at Johns Hopkins University, who was involved in an unsuccessful push for a human challenge trial involving the Zika virus, said one problem for the COVID-19 challenge could be determining how much of the virus to expose participants to in order to develop a detectable illness.

CLICK HERE FOR COMPLETE CORONAVIRUS COVERAGE 

“What are your endpoints going to be?” she said, speaking to Stat News. “You know, do you want to give people pneumonia? I hope not. You want people who feel crappy to some extent, who definitely know they’re sick. And what that balance is or what that line is between just feeling crappy and then developing pneumonia, I think one of the scary things is we really don’t know what that is.”

Morrison told Nature that volunteers typically “recognize the risk but believe the benefits of vaccine acceleration are so tremendous that it is worth it to them.”

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Hot Topics

City of Cape Town urges people to leave Kataza the baboon alone

Kataza the baboon. Facebook / Baboon Matters The City of Cape Town has asked the public not to feed a baboon that has relocated to Tokai. The baboon, known as Kataza or SK11, is slowly being integrated into the Tokai troop. Video footage, however, shows humans feeding Kataza. The City of Cape Town has requested that Kataza…

Rassie: There are various benefits for SA rugby to go north

As SA Rugby moves to determine which franchises will go to Europe in future, Rassie Erasmus has noted several potential benefits for the local game should that route be followed.The national director of rugby believes the high world rankings of Wales, Ireland and Scotland mean PRO Rugby is competitive and that fans will eventually identify…

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(John Finney Photography/Moment/Getty Images) An abnormally bad season of weather may have had a significant impact on the death toll from both World War I and the 1918 Spanish flu pandemic, according to new research, with many more lives being lost due to torrential rain and plummeting temperatures. Through a detailed analysis of an ice…

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City of Cape Town urges people to leave Kataza the baboon alone

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Rassie: There are various benefits for SA rugby to go north

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A Once-in-a-Century Climate ‘Anomaly’ Might Have Made World War I Even Deadlier

(John Finney Photography/Moment/Getty Images) An abnormally bad season of weather may have had a significant impact on the death toll from both World War I and the 1918 Spanish flu pandemic, according to new research, with many more lives being lost due to torrential rain and plummeting temperatures. Through a detailed analysis of an ice…